货号 | 4565S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Mouse |
应用 | W/IP |
目标/特异性 | Dynamin-I (3G4B6) Mouse mAb detects endogenous levels of total dynamin-I protein. |
使用方法 | WB(1:1000) IP (1:200) |
供应商 | CST |
背景 | Dynamin is a family of large GTPases that has been implicated in the formation of vesicles of both the endocytotic and secretory processes (1). Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the response to extracellular signals. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCγ, PKC and G-proteins. PKC and Src phosphorylate dynamin, and its phosphorylation may regulate the endocytosis of cell surface receptors (2,3). |
存放说明 | -20C |
计算分子量 | 100 |
Western blot analysis of extracts from various cell types using Dynamin-I (3G4B6) Mouse mAb. 对多个细胞系抽提物使用Dynamin-I (3G4B6) Mouse mAb进行Western blot分析。 |