eIF5 (D5G9) Rabbit mAb
货号：
13894S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 13894S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Eukaryotic translation initiation factor 5 (eIF5) is crucial for the assembly of translation initiation complex and plays an important role in protein synthesis (1). eIF5 interacts with the 43S initiation complex to stimulate hydrolysis of GTP bound to eIF2 (1-3). Studies suggest that eIF5 functions as the GTPase-activating protein (GAP) in the hydrolysis of GTP-bound eIF2 (4,5). This hydrolysis leads to the release of initiation factors from the 40S ribosomal subunit, which is a necessary step in the formation of the 80S initiation complex (1). |
| 存放说明 | -20C |
| 计算分子量 | 58 |
参考图片Western blot analysis of extracts from various cell lines using eIF5 (D5G9) Rabbit mAb. |
Western blot analysis of extracts from Huh7 cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-), eIF5 siRNA I (+), or eIF5 siRNA II (+), using eIF5 (D5G9) Rabbit mAb (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). The eIF5 (D5G9) Rabbit mAb confirms silencing of eIF5 expression, while the GAPDH (D16H11) XP® Rabbit mAb is used as a loading control. |
