Endoglin (D50G1) Rabbit mAb
货号：
4335S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4335S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Endoglin (D50G1) Rabbit mAb detects endogenous levels of total endoglin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways (1,2). Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos (1-4). Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure (5,6). The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer (4-6). |
| 存放说明 | -20C |
| 计算分子量 | 95 |
参考图片Western blot analysis of extracts from HUVEC cells using Endoglin (D50G1) Rabbit mAb.使用Endoglin (D50G1) Rabbit mAb对HUVEC细胞提取物进行western blot分析。 |
