EPAC1 (5D3) Mouse mAb
货号:
4155S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4155S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Mouse |
应用 | W |
目标/特异性 | Epac1 (5D3) Mouse mAb detects endogenous levels of total Epac1 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA) (reviewed in 1). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation (2), exocytosis (3), insulin signaling (4), axon growth and guidance (5) and neurotransmitter release (6). |
存放说明 | -20C |
计算分子量 | 100 |
参考图片Western blot analysis of extracts from C2C12 cells and whole rat brain using Epac1 (5D3) Mouse mAb. 使用Epac1 (5D3) Mouse mAb,免疫印迹(Western Blot)分析C2C12细胞和完整的大鼠大脑组织中Epac1 (5D3)蛋白水平。 |