EPAC2 (5B1) Mouse mAb
货号：
4156S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4156S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | EPAC2 (5B1) Mouse mAb detects endogenous levels of total EPAC2 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA) (reviewed in 1). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation (2), exocytosis (3), insulin signaling (4), axon growth and guidance (5) and neurotransmitter release (6). |
| 存放说明 | -20C |
| 计算分子量 | 115 |
参考图片Western blot analysis of extracts from mouse and rat whole brain using EPAC2 (5B1) Mouse mAb. 使用EPAC2 (5B1) Mouse mAb，免疫印迹（Western Blot）分析小鼠和大鼠完整大脑组织中EPAC2 (5B1)蛋白水平。 |
