| 货号 | 2942S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Mouse |
| 应用 | W/IP |
| 目标/特异性 | FAAH1 (L14B8) Mouse mAb detects endogenous levels of total FAAH1 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse (1). Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid (2). This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation (2). Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo (3). FAAH1 null mice also demonstrate an increased preference for alcohol and an increased voluntary uptake of alcohol as compared to wild-type mice, indicating a role of FAAH1 in modulating addictive behaviors (1). |
| 存放说明 | -20C |
| 计算分子量 | 60 |
Western blot analysis of extracts from human brain using FAAH1 (L14B8) Mouse mAb. 对人脑使用FAAH1 (L14B8) Mouse mAb鼠单抗进行Western blot分析。 | |
Western blot analysis of extracts from mouse brain using FAAH1 (L14B8) Mouse mAb. 对小鼠脑使用FAAH1 (L14B8) Mouse mAb鼠单抗进行Western blot分析。 |
