| 货号 | 13347S |
| 反应种属 | Human/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IF-IC |
| 目标/特异性 | FABP7 (D8N3N) Rabbit mAb recognizes endogenous levels of total FABP7 protein. |
| 使用方法 | WB(1:1000) IF-IC (1:2000) |
| 供应商 | CST |
| 背景 | Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). Differential expression of FABPs is found in several types of tumors and their normal-cell counterparts (3). FABP7 is abundantly expressed in fetal brain and may be essential for development (4). Expression is required for the establishment of the radial glial fiber system, a system that is necessary for the development of cortical layers (5). Increased expression of FABP7 is associated with reduced survival in patients with glioblastoma (6), and is also found in glial cells following nerve injury (7). Investigators have found loss of FABP7 may be involved in the development and progression of breast cancer and expression of FABP7 has been shown to induce mammary differentiation and to inhibit growth of breast cancer cells (8,9). |
| 存放说明 | -20C |
| 计算分子量 | 15 |
Western blot analysis of extracts from U-251 MG, SK-MEL-5, and A549 cells using FABP7 (D8N3N) Rabbit mAb (upper), and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). A549 extract is negative, as expected. Western blot分析U-251 MG、SK-MEL-5和 A549细胞提取物，使用的抗体是FABP7 (D8N3N) Rabbit mAb 兔单抗(上)和GAPDH (D16H11) XP® Rabbit mAb 兔单抗#5174 (下)。如预期所示，A549细胞提取物是阴性的。 | |
