| 货号 | 2639S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IF-IC |
| 目标/特异性 | Fibrillarin (C13C3) Rabbit mAb detects endogenous levels of total fibrillarin protein. |
| 使用方法 | WB(1:1000) IF-IC (1:400) |
| 供应商 | CST |
| 背景 | Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place (1,2). Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence (3,4). The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development (5). |
| 存放说明 | -20C |
| 计算分子量 | 37 |
Confocal immunofluorescent analysis of HeLa cells using Fibrillarin (C13C3) Rabbit mAb (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye). 使用Fibrillarin (C13C3) Rabbit mAb (绿色)标记，共聚焦免疫荧光分析HeLa细胞。Alexa Fluor® 555 phalloidin标记微丝蛋白（红色）。蓝色伪彩= DRAQ5™（DNA荧光染料）。 | |
Western blot analysis of extracts from various cell types using Fibrillarin (C13C3) Antibody. 使用Fibrillarin (C13C3) Antibody，免疫印迹（Western Blot）分析不同细胞中Fibrillarin (C13C3)蛋白水平。 |
