FIP200 (D10D11) Rabbit mAb【科瑞奥博】

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FIP200 (D10D11) Rabbit mAb

货号： 12436S 基本售价： 3360.0 元规格： -

产品信息

概述
货号	12436S
反应种属	Human/Mouse
来源宿主	Rabbit
应用	W/IP
目标/特异性	FIP200 (D10D11) Rabbit mAb recognizes endogenous levels of total FIP200 protein.
使用方法	WB(1:1000) IP (1:100)

性能
供应商	CST
背景	FIP200 (FAK family kinase-interacting protein of 200 kDa) was identified in a two-hybrid screen with the tyrosine kinase Pyk2 and can inhibit Pyk2 kinase activity as well as related family members (1). FIP200 was later independently identified in a multi-drug resistance screen and named RB1CC1 (RB1-inducible coiled-coil 1) due to its induction by cytotoxic stress and RB1 expression regulation (2). FIP200 function has been linked to apoptosis, cell cycle progression, cell growth, and migration (reviewed in 3). FIP200 has also recently been shown to interact with ULK1 and is required for autophagosome formation (4). FIP200 is part of an ULK1 complex along with Atg13 that is regulated by mTOR and is required for starvation induced autophagy (5-7).
存放说明	-20C
计算分子量	200

参考图片

Western blot analysis of extracts from various cell lines using FIP200 (D10D11) Rabbit mAb.

Western blot 分析不同细胞系的提取物，使用的抗体是 FIP200 (D10D11) Rabbit mAb 兔单抗。

Western blot analysis of extracts from A172 cells, untreated (-) or chloroquine-treated (50 μM, overnight; +) using FIP200 (D10D11) Rabbit mAb (upper) or α-Actinin (D6F6) XP® Rabbit mAb #6487 (lower).

Western blot 分析A172 细胞的提取物，未处理(-)或氯喹处理(50 μM, 过夜; +)，使用的抗体是：FIP200 (D10D11) Rabbit mAb 兔单抗（上图），或者 α-Actinin (D6F6) XP® Rabbit mAb 兔单抗#6487 （下图）。

Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expresssing full-length human FIP200 (hFIP200; +), using FIP200 (D10D11) Rabbit mAb.

Western blot分析 293T 细胞的提取物，对照转染(-)或全长的人 FIP200(hFIP200; +)载体转染，使用的抗体是FIP200 (D10D11) Rabbit mAb 兔单抗。

Immunoprecipitation of FIP200 from JJN-3 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or FIP200 (D10D11) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using FIP200 (D10D11) Rabbit mAb.

免疫沉淀分析JJN-3 细胞中提取的FIP200，使用的抗体是：Rabbit (DA1E) mAb IgG XP® Isotype Control #3900（泳道2），FIP200 (D10D11) Rabbit mAb（泳道3）。泳道1是10% input。Western blot分析使用的抗体是FIP200 (D10D11) Rabbit mAb 兔单抗。