Flotillin-2 (C42A3) Rabbit mAb
货号：
3436S 基本售价：
3360.0 元 规格：
100ul
产品信息
概述| 货号 | 3436S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 目标/特异性 | Flotillin-2 (C42A3) Rabbit mAb detects endogenous levels of total flotillin-2 protein. |
| 使用方法 | WB(1:1000)
IP (1:100) |
性能| 供应商 | CST |
| 背景 | Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry a evolutionarily conserved domain called the prohibitin homology domain (PHB) (1). Flotillin members are ubiquitously expressed and located to non-caveolar microdomains (lipid rafts) on the cell plasma membrane where they support signal transduction and regulate lipid raft motility and localization (2-5). Two flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found at compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, as well as the nucleus (6,7). Flotillin-2 is mainly localized to the plasma membrane and is prevalent in cell-cell contact sites. However, overexpressed flotillin-2 has also been found in the late endosome (4,8,9). Both flotillin-1 and flotillin-2 are commonly used as lipid raft associated markers. |
| 存放说明 | -20C |
| 计算分子量 | 49, 58 |
参考图片Western blot analysis of extracts from various cell lines using Flotillin-2 (C42A3) Rabbit mAb.使用Flotillin-2 (C42A3) Rabbit mAb，免疫印迹（Western Blot）分析不同细胞中Flotillin-2蛋白水平。 |
