| 货号 | 4567S |
| 反应种属 | Human/Mouse/Rat/Hamster/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Fumarase (D9C5) Rabbit mAb recognizes endogenous levels of total fumarase protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 背景 | Fumarate hydratase (Fumarase, FH) is canonically regarded as a mitochondrial enzyme of the tricarboxylic acid cycle that catalyzes fumarate to malate (1,2). Studies have demonstrated that deficiencies in FH can lead to hereditary leiomyomatosis and renal cell cancer (1,3) or, in homozygous germline mutations, severe neurological and muscular disorders (1,2). There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair (3). |
| 存放说明 | -20C |
| 计算分子量 | 49 |
Western blot analysis of extracts from various cell lines using Fumarase (D9C5) Rabbit mAb. 对多个细胞系使用Fumarase (D9C5)兔单克隆抗体进行Western blot分析。 | |
Western blot analysis of extracts from 293 cells, untransfected (-) or transfected with a Myc-tagged cDNA expression construct encoding human fumarase (hFumarase-Myc; +), using Fumarase (D9C5) Rabbit mAb (upper) and Myc-Tag (71D10) Rabbit mAb #2278 (lower). |
