G6PD (D5D2) Rabbit mAb
货号：
12263S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12263S |
| 反应种属 | Human/Mouse/Rat/Hamster/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | G6PD (D5D2) Rabbit mAb recognizes endogenous levels of total G6PD protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Glucose-6-phosphate dehydrogenase (G6PD) catalyses the first and rate-limiting step of the pentose phosphate pathway (1). The NADPH generated from this reaction is essential to protect cells from oxidative stress (1). Recent studies have shown that p53 interacts with G6PD and inhibits its activity, therefore suppressing glucose consumption through the pentose phosphate pathway (2). In cancer cells with p53 mutations, the increased glucose consumption is directed towards increased biosynthesis, which is critical for cancer cell proliferation (2). |
| 存放说明 | -20C |
| 计算分子量 | 58 |
参考图片Western blot analysis of extracts from various cell lines using G6PD (D5D2) Rabbit mAb. Wetern blot检测多种细胞系提取物，所用抗体为G6PD (D5D2) Rabbit mAb兔单抗。 |
