| 货号 | 8945S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-F |
| 目标/特异性 | GAP43 (D9C8) Rabbit mAb recognizes endogenous levels of total GAP43 protein. |
| 使用方法 | WB(1:1000) IP (1:50) IF-F (1:200) |
| 供应商 | CST |
| 背景 | GAP43 is a nervous system specific, growth-associated protein enriched in growth cones and areas of high plasticity (1). Phosphorylation of GAP43 at Ser41 by PKC is regulated by intracellular Ca2+ and affects the ability of GAP43 to bind calmodulin (2,3). GAP43 is integral to growth cone formation, neurite outgrowth, and the development of a functional cerebral cortex (4,5). Aberrant GAP43 expression can be seen in patients diagnosed with schizophrenia and Alzheimers disease (6,7). |
| 存放说明 | -20C |
| 计算分子量 | 38, 43 |
Confocal immunofluorescent analysis of rat hippocampus (left) and retina (right) using GAP43 (D9C8) Rabbit mAb (green) and GFAP (GA5) Mouse mAb (Alexa Fluor® 555 Conjugate) #3656 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 共聚焦免疫荧光分析大鼠海马（左）、视网膜（右），使用GAP43 (D9C8) Rabbit mAb 兔单抗（绿色）和GFAP (GA5) Mouse mAb (Alexa Fluor® 555 Conjugate) #3656（红色）进行标记。蓝色伪彩=DRAQ5® #4084(荧光DNA染料)。 | |
Western blot analysis of extracts from mouse neonatal brain and rat fetal brain using GAP43 (D9C8) Rabbit mAb. Western blot分析新生小鼠大脑和胎大鼠大脑，使用的抗体是GAP43 (D9C8)Rabbit mAb 兔单抗。 |
