| 货号 | 2643S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W/IP |
| 目标/特异性 | GLI1 (L42B10) Mouse mAb detects endogenous levels of total GLI1 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | GLI was first identified as a gene amplified in a malignant glioma (1) capable of transforming primary cells in cooperation with adenovirus E1A (2). GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2 and GLI3 (3). These GLI proteins are similar to the Drosophila homolog Ci (Cubitus interruptus) and function as transcription factors activated by the Hedgehog signaling pathway. Hedgehog signaling plays an important role in animal development and is aberrantly activated in many types of cancers (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 160 |
Western blot analysis of extracts from RMS-13 and TOV-112D cells using GLI1 (L42B10) Mouse mAb. 使用GLI1 (L42B10)Mouse mAb鼠单抗对RMS-13和TOV-112D细胞提取物进行western blot分析。 |
