| 货号 | 36877S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Rabbit IgG |
| 应用 | W/IP |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Cytoplasmic 3-hydroxy-3-methylglutaryl-CoA synthase (HMGCS1) catalyzes the first committed step of mevalonate pathway essential for cholesterol metabolism (1). HMGCS1 transcription is regulated by sterol levels (2). Recent studies showed that miR-223 reduces cholesterol biosynthesis by inhibiting HMGCS1 and methylsterol monooxygenase 1 (3). |
| 存放说明 | -20C |
| 计算分子量 | 57 |
Western blot analysis of extracts from various cell lines using HMGCS1 (D5W8F) Rabbit mAb. | |
Immunoprecipitation of HMGCS1 from Hep G2 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is HMGCS1 (D5W8F) Rabbit mAb. Western blot analysis was performed using HMGCS1 (D5W8F) Rabbit mAb. Mouse Anti-rabbit IgG (Conformation Specific) (L27A9) mAb (HRP Conjugate) #5127 was used as the secondary antibody. |
