| 货号 | 5853S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | HO-1 (D60G11) Rabbit mAb recognizes endogenous levels of total HO-1 protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme that results in the release of carbon monoxide, iron, and biliverdin (1). The products of this enzymatic reaction play important biological roles in antioxidant, anti-inflammatory and cytoprotective functions (2). Heme oxygenase comprises two isozymes, including the constitutively expressed HO-2 isozyme and the inducible HO-1 isozyme (3). Inducible HO-1 is expressed as an adaptive response to several stimuli, including heme, metals, and hormones (4). The induction of HO-1 has been implicated in numerous disease states, such as transplant rejection, hypertension, atherosclerosis, Alzheimer disease, endotoxic shock, diabetes, inflammation, and neurological disorders (1,5). |
| 存放说明 | -20C |
| 计算分子量 | 28 |
Western blot analysis of extracts from HeLa cells, untreated or Arsenic-treated, using HO-1 (D60G11) Rabbit mAb. Wetern blot检测hela细胞系提取物，未处理或用Arsenic处理，所用抗体为HO-1 (D60G11) Rabbit mAb兔单抗 |
