HSD17B6 (D1T5H) Rabbit mAb
货号：
14669S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 14669S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The type 6 17-β-hydroxysteroid dehydrogenase (HSD17B6, 17-β-HSD 6) regulates cellular hydroxysteroids by catalyzing the conversion of androsterone to epiandrosterone (1). This enzyme displays both oxidoreductase and epimerase activities, and is also known as 3(α->β)-hydroxysteroid epimerase. The interaction between HSD17B6 and hydroxysteroid compounds has an important effect on steroid activity as these compounds typically act in a stereo-specificity manner (1). Research studies show that the transcriptional activity of androgen receptor in prostate cell lines treated by androstanediol correlates with HSD17B6 protein level, which suggests an important role for enzyme in prostate cancer growth (2). |
| 存放说明 | -20C |
| 计算分子量 | 29 |
参考图片Western blot analysis of extracts from human liver (positive), kidney (negative), and colon (negative) tissues using HSD17B6 (D1T5H) Rabbit mAb (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). |
