Id2 (D39E8) Rabbit mAb
货号：
3431S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3431S |
| 反应种属 | Human/Mouse/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Id2 (D39E8) Rabbit mAb detects endogenous levels of total Id2 protein. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Inhibitor of DNA-binding-2 (Id2) is a member of the Id proteins which belong to the helix-loop-helix (HLH) protein family. The Id protein functions by binding to specific transcription factors and preventing their dimerization and DNA binding (1-3). Id2 interacts with a wide variety of transcription factors including E proteins (5), TCS (4), Pax (6) and the tumor suppressor Rb (1). Id2 has been shown to be important in regulating cellular differentiation, proliferation, development and tumorgenesis (7-9). In tumor cells, increased levels of Id2 functionally inactivate Rb, leading to cellular transformation and cancer (10,11). Id2 is therefore a promising therapeutic target for treatment of cancer (12). |
| 存放说明 | -20C |
| 计算分子量 | 15 |
参考图片Western blot analysis of extracts from various cell lines using Id2 (D39E8) Rabbit mAb.使用Id2 (D39E8) 兔单抗对多种细胞提取物进行western blot分析。 |
