| 货号 | 3014S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | IHC-P/IF-F/IF-IC/F |
| 目标/特异性 | Insulin (C27C9) Rabbit mAb detects endogenous levels of total insulin protein. |
| 使用方法 | IHC-P(1:400) F (1:50) IF-F (1:800) IF-IC (1:200) |
| 供应商 | CST |
| 背景 | The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into the skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2). |
| 存放说明 | -20C |
| 计算分子量 | 6 |
Confocal immunofluorescent analysis of β-TC-6 (left) and C2C12 cells (right) using Insulin (C27C9) Rabbit mAb (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).对β-TC-6细胞(左)和C2C12细胞(右)使用Insulin (C27C9) Rabbit mAb（绿色）进行共聚焦免疫荧光分析。肌动蛋白用DY-554 phalloidin（红色）标记。蓝色伪彩=DRAQ5?#4084(荧光DNA染料)。 | |
Flow cytometric analysis of HeLa cells (blue) and β-TC-6 cells (green) using Insulin (C27C9) Rabbit mAb.对HeLa（蓝）和β-TC-6（绿）细胞使用Insulin (C27C9) Rabbit mAb进行流式细胞仪分析。 | |
Immunohistochemical analysis of paraffin-embedded rat pancreas, showing staining of β cells, using Insulin (C27C9) Rabbit mAb.对石蜡包埋的大鼠胰腺使用Insulin (C27C9) Rabbit mAb进行免疫组化分析，显示β细胞染色。 | |
Immunohistochemical anaylsis of paraffin-embedded mouse pancreas, showing staining of β cells, using Insulin (C27C9) Rabbit mAb.对石蜡包埋的小鼠胰腺使用Insulin (C27C9) Rabbit mAb进行免疫组化分析，显示β细胞染色。 | |
Immunohistochemical analysis of paraffin-embedded human pancreas, showing the staining of β cells, using Insulin (C27C9) Rabbit mAb.对石蜡包埋的人胰腺使用Insulin (C27C9) Rabbit mAb进行免疫组化分析，显示β细胞染色。 | |
Confocal immunofluorescent analysis of rat pancreas using Insulin (C27C9) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).对大鼠胰腺使用Insulin (C27C9) Rabbit mAb（绿色）进行共聚焦免疫荧光分析。蓝色伪彩=DRAQ5?#4084(荧光DNA染料)。 |
