货号 | 13807S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:100) |
供应商 | CST |
背景 | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2). |
存放说明 | -20C |
计算分子量 | 137 |
Western blot analysis of extracts from various cell lines using Integrin α2b (D8V7H) Rabbit mAb (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). As expected, K-562 and HL-60 are negative for integrin α2b. | |
Immunoprecipitation of Integrin α2b from OCI-M1 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or Integrin α2b (D8V7H) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using Integrin α2b (D8V7H) Rabbit mAb. |