IκBβ (7B4) Mouse mAb
货号：
8635S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8635S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | IκBβ (7B4) Mouse mAb recognizes endogenous levels of total IκBβ protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8). |
| 存放说明 | -20C |
| 计算分子量 | 48 |
参考图片Western blot analysis of extracts from MCF7 cells, untreated (-) or treated with Human Tumor Necrosis Factor-α (hTNF-α) #8902 (20 ng/ml, 4 hr; +), using IκBβ (7B4) Mouse mAb (upper) and α-Tubulin (11H10) Rabbit mAb #2125 (lower).Western免疫印迹。用IκBβ (7B4) Mouse mAb (上图)和α-Tubulin (11H10) Rabbit mAb #2125 (下图)研究未经处理 (-) 和经hTNF-α) #8902 (20 ng/ml, 4 hr; +)处理的MCF7细胞的细胞提取液。 |
Western blot analysis of extracts from various cell lines using IκBβ (7B4) Mouse mAb.Western免疫印迹。用IκBβ (7B4) Mouse mAb研究各种细胞系的细胞提取液。 |
