| 货号 | 3344S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IHC-P |
| 目标/特异性 | Jak1 (6G4) Rabbit mAb detects endogenous levels of total Jak1 protein. It does not cross react with other Jak family members. |
| 使用方法 | WB(1:1000) IHC-P (1:100) |
| 供应商 | CST |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | -20C |
| 计算分子量 | 130 |
Western blot analysis of extracts from ACHN, SR, CTLL-2 and PC12 cell lines using Jak1 (6G4) Rabbit mAb.Western免疫印迹。用Jak1 (6G4) Rabbit mAb研究ACHN, SR, CTLL-2 和 PC12细胞系的细胞提取液。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Jak1 (6G4) Rabbit mAb. 免疫组织化学染色分析石蜡包埋人肺癌细胞组织。所用抗体为 Jak1 (6G4) Rabbit mAb。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Jak1 (6G4) Rabbit mAb.免疫组织化学染色分析石蜡包埋人乳腺癌组织。所用抗体为 Jak1 (6G4) Rabbit mAb。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Jak1 (6G4) Rabbit mAb #3344, in the presence of control peptide (left) or Jak1 Blocking Peptide (right).免疫组织化学染色分析石蜡包埋人乳腺癌组织。在对照多肽(左图) 或 Jak1 封闭多肽(右图)存在下所用抗体为 Jak1 (6G4) Rabbit mAb#3344。 |
