Keratin 18 (DC10) Mouse mAb【科瑞奥博】

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Keratin 18 (DC10) Mouse mAb

货号： 4548S 基本售价： 3360.0 元规格： 100ul

产品信息

概述
货号	4548S
反应种属	Human
来源宿主	Mouse
应用	W/IHC-P/IF-IC/F
目标/特异性	Keratin 18 (DC10) Mouse mAb detects endogenous levels of total keratin 18 protein. The antibody does not cross-react with other keratins.
使用方法	WB(1:2000) IHC-P (1:500) F (1:2000) IF-IC (1:800)

性能
供应商	CST
背景	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).
存放说明	-20C
计算分子量	46

参考图片

Western blot analysis of extracts from HeLa and A431 cells, using Keratin 18 (DC10) Mouse mAb.使用Keratin 18 (DC10) Mouse mAb，免疫印迹（Western Blot）分析HeLa和A431细胞中Keratin 18蛋白水平。

Immunohistochemical analysis of paraffin-embedded human breast carcinoma, showing cytoplasmic localization using Keratin 18 (DC10) Mouse mAb.使用Keratin 18 (DC10) Mouse mAb，免疫组化分析人源乳腺癌组织石蜡切片，结果显示定位于细胞质。

Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using Keratin 18 (DC10) Mouse mAb.使用Keratin 18 (DC10) Mouse mAb，免疫组化分析人源肺癌组织石蜡切片。

Immunohistochemical analysis of paraffin-embedded human benign prostate hyperplasia, using Keratin 18 (DC10) Mouse mAb.使用Keratin 18 (DC10) Mouse mAb，免疫组化分析人源前列腺良性增生组织石蜡切片。

Flow cytometric analysis of HeLa cells, using Keratin 18 (DC10) Mouse mAb (blue) compared to a nonspecific negative control antibody (red).与非特异阴性control antibody (红色)比较，使用Keratin 18 (DC10) Mouse mAb (蓝色)标记，流式细胞仪分析HeLa细胞。

Confocal immunofluorescent analysis of HepG2 (left) and SH-SY5Y (right) cells using Keratin 18 (DC10) Mouse mAb (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用Keratin 18 (DC10) Mouse mAb (绿色)标记，共聚焦免疫荧光观察Keratin 18蛋白在HepG2 (左图)和SH-SY5Y (右图)细胞中定位。DY-554 phalloidin标记微丝蛋白（红色）。蓝色=DRAQ5®#4084(DNA荧光染料)。