| 货号 | 9449S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | IHC-P/IF-IC/F |
| 使用方法 | IHC-P(1:400) F (1:400) IF-IC (1:800) |
| 供应商 | CST |
| 背景 | Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).Ki-67，以其发现地命名（Kiel大学，德国），作为一个细胞核非组蛋白（1）通常在增殖的细胞中表达并且在休眠细胞中不表达（2）。Ki-67会让增殖细胞停滞在G1，S，G2和有丝分裂期，但是不会停滞在G0期。研究显示高表达的Ki-67与低乳腺癌存活率相关（3）。研究已经将Ki-67与其他的标记，作为乳腺癌和其他恶性疾病中的潜在的预后和预测标记（4）。 |
| 存放说明 | -20C |
Confocal immunofluorescent analysis of HeLa cells using Ki-67 (8D5) Mouse mAb (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用Ki-67 (8D5) 小鼠mAb（绿色）对HeLa细胞进行激光共聚焦免疫荧光分析。肌动蛋白丝使用DY-554鬼笔环肽标记（红色）。蓝色假色= DRAQ5® #4084 (fluorescent DNA dye). | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Ki-67 (8D5) Mouse mAb.使用Ki-67 (8D5) 小鼠mAb对石蜡包埋的人乳腺癌组织进行免疫组化分析。 | |
Flow cytometric analysis of Jurkat cells using Ki-67 (8D5) Mouse mAb and Propidium Iodide (PI)/RNase Staining Solution #4087.使用Ki-67 (8D5) 小鼠mAb和碘化丙啶（PI）/RNase固定液#4087对Jurkat细胞进行流式细胞分析。 | |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Ki-67 (8D5) Mouse mAb.使用Ki-67 (8D5) 小鼠mAb对石蜡包埋的人结肠癌组织进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded human ovarian serous adenocarcinoma using Ki-67 (8D5) Mouse mAb. 使用Ki-67 (8D5) 小鼠mAb对石蜡包埋的人卵巢癌组织进行免疫组化分析。 |
