货号 | 12202S |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | IHC-P |
使用方法 | IHC-P(1:400) |
供应商 | CST |
背景 | Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4). Ki-67,以其发现地命名(Kiel大学,德国),作为一个细胞核非组蛋白(1)通常在增殖的细胞中表达并且在休眠细胞中不表达(2)。Ki-67会让增殖细胞停滞在G1,S,G2和有丝分裂期,但是不会停滞在G0期。研究显示高表达的Ki-67与低乳腺癌存活率相关(3)。研究已经将Ki-67与其他的标记,作为乳腺癌和其他恶性疾病中的潜在的预后和预测标记(4)。 |
存放说明 | -20C |
Immunohistochemical analysis of paraffin-embedded mouse spleen using Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated).使用Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated)对石蜡包埋的小鼠脾脏组织进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded mouse colon using Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated).使用Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated)对石蜡包埋的小鼠结肠组织进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded mouse heart using Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated). Heart is negative, as expected.使用使用Ki-67 (D3B5) Rabbit mAb (Mouse Specific; IHC Formulated)对石蜡包埋的小鼠心脏组织进行免疫组化分析。如预期,心脏不表达Ki-67。 |