Lamin B1 (D4Q4Z) Rabbit mAb
货号：
12586S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12586S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Lamins are nuclear membrane structural components that are important in maintaining normal cell functions, such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamins have been subdivided into types A and B. Type-A lamins consist of lamin A and C, which arise from alternative splicing of the lamin A gene LMNA. Lamin A and C are cleaved by caspases into large (41-50 kDa) and small (28 kDa) fragments, which can be used as markers for apoptosis (4,5). Type-B lamins consist of lamin B1 and B2, encoded by separate genes (6-8). Lamin B1 is also cleaved by caspases during apoptosis (9). Research studies have shown that duplication of the lamin B1 gene LMNB1 is correlated with pathogenesis of the neurological disorder adult-onset leukodystrophy (10). |
| 存放说明 | -20C |
| 计算分子量 | 68, 25 |
参考图片Western blot analysis of extracts from HeLa cells, untreated or treated with Staurosporine #9953 (1 μM, 3 hr), using Lamin B1 (D4Q4Z) Rabbit mAb. Western blot 检测HeLa细胞提取物，未处理或Staurosporine #9953（1 μM, 3 hr）处理，使用抗体为Lamin B1 (D4Q4Z) Rabbit mAb。 |
Western blot analysis of extracts from various cell lines using Lamin B1 (D4Q4Z) Rabbit mAb. Western blot 检测多种细胞系提取物，使用抗体为Lamin B1 (D4Q4Z) Rabbit mAb。 |
