LAMP1 (C54H11) Rabbit mAb
货号：
3243S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3243S |
| 反应种属 | Human/Mouse/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | LAMP1 (C54H11) Rabbit mAb detects endogenous levels of total LAMP1 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis (3). The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes (4). LAMP1 and LAMP2 are 37% homologous in their protein sequences. The cellular functions of these two proteins are also overlap - both are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking (5,6). |
| 存放说明 | -20C |
| 计算分子量 | 42 (non-glycosylated), 90-120 (glycosylated) |
参考图片Western blot analysis of extracts from HeLa, Neuro2a and COS cells using LAMP1 (C54H11) Antibody. 使用LAMP1 (C54H11) Antibody，免疫印迹（Western Blot）分析HeLa、Neuro2a和COS细胞中LAMP1蛋白水平。 |
