| 货号 | 8145S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | LAMTOR2/ROBLD3 (D7C10) Rabbit mAb recognizes endogenous levels of total LAMTOR2/ROBLD3 protein. This antibody may cross-react with LAMTOR1/C11orf59 and LAMTOR3/MAPKSP1. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | mTORC1 kinase complex is a critical component in the regulation of cell growth (1,2). Its activity is modulated by energy levels, growth factors, and amino acids (3,4). The four related GTPases, RagA, RagB, RagC, and RagD, have been shown to interact with raptor in mTORC1 (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). A protein complex consisting of LAMTOR1/C11orf59, LAMTOR2/ROBLD3, and LAMTOR3/MAPKSP1 has been identified to interact with and recruit the four Rag GTPases to the surface of lysosomes (5). |
| 存放说明 | -20C |
| 计算分子量 | 14 |
Western blot analysis of extracts from various cell lines using LAMTOR2/ROBLD3 (D7C10) Rabbit mAb. Western blot分析不同细胞系裂解物，所用抗体为LAMTOR2/ROBLD3 (D7C10) Rabbit mAb兔单抗。 |
