MAG (D10H1) Rabbit mAb
货号：
12275S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12275S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | MAG (D10H1) Rabbit mAb recognizes endogenous levels of total MAG protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Myelin-associated glycoprotein (MAG), which contains five immunoglobulin-like domains, is a highly glycosylated protein (1). MAG is a component of all myelinated internodes, whether formed by oligodendrocytes in the central nervous system (CNS) or by Schwann cells in the peripheral nervous system (PNS) (2), and has several functions. A known function of MAG is its inhibition of axonal regeneration after injury. It inhibits axonal outgrowth from adult dorsal root ganglion and in postnatal cerebellar, retinal, spinal, hippocampal, and superior cervical ganglion neurons (3). Interaction between MAG and several other molecules on the innermost wrap of myelin and complementary receptors on the opposing axon surface are required for long-term axon stability. Without MAG, myelin is still expressed, but long-term axon degeneration and altered axon cytoskeleton structure can be seen (4). |
| 存放说明 | -20C |
| 计算分子量 | 100 |
参考图片Western blot analysis of extracts from mouse and rat brain using MAG (D10H1) Rabbit mAb. Western blot检测小鼠和大鼠的大脑提取物，使用的抗体是MAG (D10H1) Rabbit mAb兔单抗。 |
