MKK3 (D4C3) Rabbit mAb
货号：
8535S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8535S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000)
IP (1:200) |
性能| 供应商 | CST |
| 背景 | MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines (4,5). Activation of MKK3 and MKK6 occurs through phosphorylation at Ser189 and Thr193 on MKK3 (2) and Ser207 and Thr211 on MKK6 (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 38-40 |
参考图片Western blot analysis of extracts from various cell lines using MKK3 (D4C3) Rabbit mAb. |
