MMP-2 (D8N9Y) Rabbit mAb
货号：
13132S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 13132S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors, and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7, and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis, and apoptosis (2-4). Research studies have shown that MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5). |
| 存放说明 | -20C |
| 计算分子量 | 64,72 |
参考图片Western blot analysis of concentrated, serum-free cultured medium from U-87 MG and HT-1080 cells, untreated (-) or treated with TPA (12-O-Tetradecanoylphorbol-13-Acetate) #4174 (200 nM; +), using MMP-2 (D8N9Y) Rabbit mAb.不处理(-)或经过TPA (12-O-Tetradecanoylphorbol-13-Acetate) #4174 (200 nM; +)处理的U-87 MG和HT-1080细胞无血清培养基，经浓缩后，使用MMP-2 (D8N9Y) Rabbit mAb进行western blot分析。 |
