货号 | 18339S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit IgG |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Voltage gated sodium channels are composed of a large alpha subunit and auxiliary beta subunits. The alpha subunit has 4 homologous domains, with each domain containing 6 transmembrane segments. These segments function as the voltage sensor and sodium permeable pore. Upon change of membrane potential, the sodium channel is activated, which allows sodium ions to flow through (1,2). When associated with beta subunits or other accessory proteins, the alpha subunit is regulated at the level of cell surface expression, kinetics, and voltage dependence (3,4). |
存放说明 | -20C |
计算分子量 | 250 |
Western blot analysis of membrane extracts from human, mouse and rat brain using Nav1.1 (D8X1Y) Rabbit mAb. | |
Immunoprecipitation of Nav1.1 from mouse brain extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is Nav1.1 (D8X1Y) Rabbit mAb. Western blot analysis was performed using Nav1.1 (D8X1Y) Rabbit mAb. |