Nicastrin (D38F9) Rabbit mAb
货号：
5665S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 5665S |
| 反应种属 | Human/Mouse/Rat/Hamster/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Nicastrin (D38F9) Rabbit mAb recognizes endogenous levels of total Nicastrin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Nicastrin is a transmembrane glycoprotein serving as an essential component of the γ-secretase complex (1,2). Nicastrin is physically associated with presenilin and plays an important role in the stabilization and correct localization of presenilin to the membrane-bound γ-secretase complex (3). Nicastrin also serves as a docking site for γ-secretase substrates such as APP and Notch, directly binding to them and properly presenting them to γ-secretase to ensure the correct cleavage process (2,4). |
| 存放说明 | -20C |
| 计算分子量 | 110, 120 |
参考图片Western blot analysis of extracts from various cell lines using Nicastrin (D38F9) Rabbit mAb. Western blot分析多个细胞系提取物，使用的抗体是Nicastrin (D38F9) Rabbit mAb 兔单抗。 |
