Nicastrin (D65G7) Rabbit mAb
货号：
9447S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9447S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Nicastrin is a transmembrane glycoprotein serving as an essential component of the γ-secretase complex (1,2). Nicastrin is physically associated with presenilin and plays an important role in the stabilization and correct localization of presenilin to the membrane-bound γ-secretase complex (3). Nicastrin also serves as a docking site for γ-secretase substrates such as APP and Notch, directly binding to them and properly presenting them to γ-secretase to ensure the correct cleavage process (2,4). |
| 存放说明 | -20C |
| 计算分子量 | 110, 120 |
参考图片Western blot analysis of extracts from NIH/3T3 and CAD cells using Nicastrin (D65G7) Rabbit mAb. |
