| 货号 | 13829S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins is a diverse family of cytoplasmic innate immune receptors. They are characterized by the presence of an amino-terminal effector domain, which is often either a caspase activation and recruitment domain (CARD) or a pyrin domain (PYD), followed by a NACHT domain and carboxy-terminal leucine-rich-repeats (LRR) involved in recognition of pathogen-associated molecular patterns (PAMPs) (1). NLR proteins play a variety of roles during the innate immune response including pathogen sensing, transcriptional activation of proinflammatory cytokines through NF-κB, transcriptional activation of type I interferons through IRFs, and formation of inflammasomes leading to activation of inflammatory caspases (1-7). |
| 存放说明 | -20C |
| 计算分子量 | 100 |
Western blot analysis of extracts from various cell lines using NLRX1 (D4M3Z) Rabbit mAb. | |
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing full-length human NLRX1 (hNLRX1, +), using NLRX1 (D4M3Z) Rabbit mAb. | |
Immunoprecipitation of NLRX1 from THP-1 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or NLRX1 (D4M3Z) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using NLRX1 (D4M3Z) Rabbit mAb. |
