| 货号 | 4231S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P/IF-F |
| 目标/特异性 | nNOS (C7D7) Rabbit mAb detects endogenous levels of total nNOS protein. |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:200) IF-F (1:200) |
| 供应商 | CST |
| 背景 | Nitric Oxide Synthase (NOS) catalyses the formation of nitric oxide (NO) and citruline from L-arginine, oxygen and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2,3). |
| 存放说明 | -20C |
| 计算分子量 | 160 |
Confocal immunofluorescent analysis of wild-type (+/+, upper) and nNOS null mouse brain (-/-, lower) using nNOS (C7D7) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 共聚焦免疫荧光分析野生型(+/+，上图)和nNOS缺失小鼠大脑(-/-，下图)，使用nNOS (C7D7) Rabbit mAb 兔单抗（绿色）进行标记。蓝色伪彩=DRAQ5® #4084(荧光DNA染料)。 | |
Western blot analysis of extracts from mouse and rat brain using nNOS (C7D7) Rabbit mAb. Western blot分析小鼠和大鼠大脑提取物，使用的抗体是nNOS (C7D7) Rabbit mAb 兔单抗。 | |
Western blot analysis of extracts from wild-type (+/+) and nNOS null (-/-) mouse brain using nNOS (C7D7) Rabbit mAb (upper) and PSD95 Antibody #2507 (lower). Western blot分析野生型 (+/+)和nNOS缺失(-/-)小鼠大脑提取物，使用的抗体是nNOS (C7D7) Rabbit mAb 兔单抗（上图）和PSD95 Antibody 兔多抗 #2507（下图）。 | |
Immunohistochemical analysis of paraffin-embedded wild-type (+/+, left) or nNOS null (-/-, right) mouse brain, using nNOS (C7D7) Rabbit mAb. 共聚焦免疫荧光分析野生型(+/+，左图)和nNOS缺失小鼠大脑(-/-，右图)，使用的抗体是nNOS (C7D7) Rabbit mAb 兔单抗。 |
