NUP88 (D7U4O) Rabbit mAb
货号：
13613S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 13613S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The nuclear pore complex (NPC) is a multi-subunit protein channel that spans the nuclear envelope and is responsible for the nucleocytoplasmic trafficking of RNA, proteins, and ribonucleoproteins (1). The 88 kDa nucleoporin protein (NUP88) is located on the cytoplasmic side of the NPC and found to be a part of a subcomplex with the NUP214 NPC subunit (1-3). This NUP88/NUP214 subcomplex interacts with CRM-1/exportin-1 to play an important role in the export of proteins, including the 60S ribosomal particle from the nucleus (4,5). Research studies demonstrate elevated expression and cytoplasmic accumulation of NUP88, visible as granular dots, in ovarian, prostate, and breast cancers (6-9). Increased NUP88 levels correlate with higher tumor grade, suggesting that NUP88 may be a putative tumor marker (1,7). |
| 存放说明 | -20C |
| 计算分子量 | 88 |
参考图片Western blot analysis of extracts from various cell lines using NUP88 (D7U4O) Rabbit mAb. |
