| 货号 | 4286S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Mouse |
| 应用 | W/IP |
| 目标/特异性 | Oct-4 (9B7) Mouse mAb detects endogenous levels of total Oct-4 protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2,3). Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that it is the Oct-4A isoform that has the ability to confer and sustain pluripotency and that Oct-4B may exist in some somatic, non-pluripotent cells (6,7). |
| 存放说明 | -20C |
| 计算分子量 | 45 |
Western blot analysis of extracts from NTERA and F9 cell lines using Oct-4 (9B7) Mouse mAb. 使用Oct-4（9B7）Mouse mAb鼠单抗对NTERA和F9细胞提取物进行western blot分析。 |
