| 货号 | 9875S |
| 反应种属 | Human/Mouse/Rat/Monkey/All |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | O-GlcNAc (CTD110.6) Mouse mAb specifically recognizes endogenous levels of O-GlcNAc on proteins in β-O-glycosidic linkage to both serine and threonine. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 背景 | O-GlcNAcylation is a post-translational modification where β-D-N-acetylglucosamine (GlcNAc) is covalently linked to cytoplasmic and nuclear proteins at serine or threonine residues (1,2). This modification is important in many cellular processes including metabolism, cell growth and morphogenesis, apoptosis and transcription (2,3) and has been implicated to play a critical role in cancer (1). |
| 存放说明 | -20C |
Western blot analysis of extracts from various cell lines using O-GlcNAc (CTD110.6) Mouse mAb. 对多个细胞系使用O-GlcNAc (CTD110.6)鼠单克隆抗体进行Western blot分析。 | |
Western blot analysis of extracts from HeLa cells in the absence or presence of PUGNAC, an inhibitor of N-acetyl-β-d-glucosaminidase, using O-GlcNAc (CTD110.6) Mouse mAb (upper) or β-Actin (13E5) Rabbit mAb #4970 (lower). 对存在或不存在PUGNA（一种N-乙酰-β-D-葡萄糖苷酶抑制剂）的HeLa细胞，使用O-GlcNAc (CTD110.6)鼠单抗（上图）或β-Actin (13E5)兔单克隆抗体#4970（下图）进行Western blot分析。 |
