货号 | 8565S |
反应种属 | Human/Monkey |
来源宿主 | Rabbit |
应用 | W/IP/IF-IC |
目标/特异性 | PCK2 (D3E11) Rabbit mAb recognizes endogenous levels of total PCK2 protein. |
使用方法 | WB(1:1000) IP (1:50) IF-IC (1:100) |
供应商 | CST |
背景 | PCK2 (PEPCK2 or PEPCK-M) encodes an isoform of phosphoenolpyruvate carboxykinase (PEPCK) that is found in the mitochondria of renal and hepatic tissues (1). PEPCK is involved in gluconeogenesis, the process of generating glucose from non-carbohydrate substrates such as lactate and glycerol (2). PEPCK catalyzes the reaction whereby oxaloacetate becomes phosphoenolpyruvate, a rate limiting step in the metabolic process (2). The predominant function of PCK2 is to process the lactate that is continually produced by red blood cells in the liver and kidney (1). |
存放说明 | -20C |
计算分子量 | 71 |
Confocal immunofluorescent analysis of HeLa cells uisng PCK2 (D3E11) Rabbit mAb (green) showing colocalization with mitochondria that were labeled with MitoTracker® Red CMXRos (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 对HeLa细胞使用PCK2 (D3E11) Rabbit mAb兔单抗(绿色)进行共聚焦免疫荧光分析显示与MitoTracker? Red CMXRos(红色)标记的线粒体共定位。蓝色伪彩=DRAQ5?#4084(荧光DNA染料)。 | |
Western blot analysis of extracts from various cell lines using PCK2 (D3E11) Rabbit mAb. 对多个细胞系使用PCK2 (D3E11)兔单克隆抗体进行Western blot分析。 |