| 货号 | 24964S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human/Mouse/Rat/Moneky |
| 来源宿主 | Rabbit IgG |
| 应用 | W IP |
| 目标/特异性 | NCBP1/CBP80 (D7Z2Z) Rabbit mAb recognizes endogenous levels of total NCBP1/CBP80 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Nuclear cap-binding protein subunit 1 (NCBP1), also known as cap-binding protein 80 (CBP80), plays a role in nuclear pre-mRNA splicing (1,2). It has also been shown to function in the nonsense-mediated decay (NMD) of mRNAs where translation is prematurely terminated (3). NCBP1/CBP80 increases the efficiency of NMD by promoting the interaction of two active NMD components Upf1 and Upf2 (4). |
| 存放说明 | -20C |
| 计算分子量 | 80 |
| 参考文献 | 1 . Izaurralde, E. et al. (1994) Cell 78, 657-68. 2 . Izaurralde, E. et al. (1995) Nature 376, 709-12. 3 . Ishigaki, Y. et al. (2001) Cell 106, 607-17. 4 . Hosoda, N. et al. (2005) Nat Struct Mol Biol 12, 893-901. |
Western blot analysis of extracts from various cell lines using NCBP1/CBP80 (D7Z2Z) Rabbit mAb. |
