| 货号 | 34971S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit IgG |
| 应用 | W IHC-P |
| 目标/特异性 | Integrin β1 (D6S1W) Rabbit mAb recognizes endogenous levels of total integrin β1 protein. |
| 使用方法 | WB(1:1000) IHC-P (1:100) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2). |
| 存放说明 | -20C |
| 计算分子量 | 115, 135 |
| 参考文献 | 1 . Liu, S. et al. (2000) J Cell Sci 113 ( Pt 20), 3563-71. 2 . Hood, J.D. and Cheresh, D.A. (2002) Nat Rev Cancer 2, 91-100. 3 . van der Flier, A. and Sonnenberg, A. (2001) Cell Tissue Res 305, 285-98. 4 . Brakebusch, C. and Fässler, R. (2005) Cancer Metastasis Rev 24, 403-11. 5 . Mettouchi, A. and Meneguzzi, G. (2006) Eur J Cell Biol 85, 243-7. |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Integrin β1 (D6S1W) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Integrin β1 (D6S1W) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human skin using Integrin β1 (D6S1W) Rabbit mAb. | |
Western blot analysis of extracts from various cell lines using Integrin β1 (D6S1W) Rabbit mAb. |
