PLA2G1B (D1T4C) Rabbit mAb
货号:
14635S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 14635S |
反应种属 | Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Phospholipase A2 (PLA2) is a superfamily of enzymes that hydrolyze glycero-3-phosphocholines and release fatty acids and lysophospholipids (1). PLA2G1B is a member of this superfamily in the 1B group that is expressed most highly in the pancreatic acinar cells (2). Evidence suggests that PLA2G1B plays a role in the absorption and storage of extra energy as fats are metabolized (1,2). Lysophospholipids generated by PLA2G1B inhibit fatty acid oxidation in the liver and reduce energy expenditure, leading to diet-induced obesity and type 2 diabetes with a high fat diet (1). Therefore, a potential intervention of obesity and diabetes could target PLA2G1B in the digestive tract (2). |
存放说明 | -20C |
计算分子量 | 16 |
参考图片Western blot analysis of extracts from mouse and rat pancreas using PLA2G1B (D1T4C) Rabbit mAb. |
Western blot analysis of 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK tagged full-length mouse PLA2G1B protein (mPLA2G1B-MycDDK; +), using PLA2G1B (D1T4C) Rabbit mAb (upper), DYKDDDDK Tag (9A3) Mouse mAb #8146 (middle), and β-Actin (D6A8) Rabbit mAb #8457 (lower). |