Plexin A2 (D44D4) Rabbit mAb
货号：
6896S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 6896S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Class 3 secreted semaphorin (Sema3A) is a chemorepellent that acts upon a wide variety of axons. As such, it induces a dramatic redistribution and depolymerization of actin filaments that results in growth cone collapse. Plexins are single membrane-spanning signaling proteins encompassing Plexin A1, A2, A3, and A4. Plexins form a complex with neuropilin-1 and -2 and the cell adhesion protein L1 to form a functional semaphorin receptor (1,2). The GTPase Rnd1 binds to the cytoplasmic domain of Plexin A1 to trigger cytoskeletal collapse. In contrast, the GTPase RhoD blocks Rnd1-mediated Plexin A1 activation and repulsion of sympathetic axons by Sema3A (3). |
| 存放说明 | -20C |
| 计算分子量 | 212 |
参考图片Western blot analysis of extracts from neonatal and adult mouse, and fetal rat brain tissue using Plexin A2 (D44D4) Rabbit mAb. Western blot分析新生和成年小鼠、胎大鼠脑组织，使用的抗体是Plexin A2 (D44D4) Rabbit mAb 兔单抗。 |
