PPP2R2A (2G9) Mouse mAb
货号:
5689S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 5689S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Mouse |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | Protein phosphatase 2A subunit B isoform R2-α (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B (1). Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways (7) and may play an important role in cell cycle regulation (2-4). PPP2R2A/PP2A, B55-α/PR55-α isoform interacts with the type I TGF-β receptors via unique WD-40 repeats (5) that contribute to the anti-proliferative function of TGF-β receptors (6).蛋白磷酸酶2A亚基B的异构体R2-α (PPP2R2A)是丝氨酸/苏氨酸蛋白磷酸酶2A(PP2A)的调节亚基B的组成部分。PPP2R2A属于调节亚基B的R2/B55/PR55家族(1)。有证据表明亚基PPP2R2A能够增强TGF-β、激活素和Nodal信号通路(7)并在细胞周期调节中发挥重要作用(2-4)。PPP2R2A/PP2A,B55-α/PR55-α异构体通过特异性的WD-40重复序列(5)和1型TGF-β受体相互作用,有助于TGF-β受体抗增殖功能的发挥(6)。 Application References |
存放说明 | -20C |
计算分子量 | 52 |
参考图片Western blot analysis of extracts from various cell lines using PPP2R2A (2G9) Mouse mAb.Western blot方法检测不同细胞提取物,使用的抗体为PPP2R2A (2G9) Mouse mAb。 |