PPP2R4 (5G3) Mouse mAb
货号：
5686S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 5686S |
| 反应种属 | Human/Mouse/Monkey |
| 来源宿主 | Mouse |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Serine/threonine protein phosphatase 2A regulatory subunit 4 (PPP2R4) is one of the constituents of the regulatory subunit B of PP2A (1). PPP2R4 is also known as the phosphatase activator (PTPA) and known to have the peptidyl prolyl isomerase (PPIase) activity (2-3). PPIases catalyze cis-trans isomerization of peptide bonds of proline residues in the polypeptide chain; this leads to the rapid folding of proteins (2). The ATPase activity of PPP2R4 is required for the phosphotyrosyl phosphatase activity of PP2A (2-4). Evidence suggests that PPP2R4 induces apoptosis independent of the canonical PP2A-mediated pathways (4).丝氨酸/苏氨酸 蛋白磷酸酶2A调节亚基4(PPP2R4)是PP2A调节亚基B的一个组分(1)。PPP2R4被认为是磷酸酶激活剂(PTPA)并且具有肽酰脯氨酰异构酶活性(2-3)。PPIases催化多肽链上脯氨酸残基肽键的顺式异构化，这导致蛋白质的快速折叠(2)。PPP2R4的ATP酶活性对于PP2A的phosphotyrosyl磷酸酶活性是必须的(2-4)。有证据表明PPP2R4诱导凋亡不依赖于经典的PP2A调节通路(4)。 Application References |
| 存放说明 | -20C |
| 计算分子量 | 40 |
参考图片Western blot analysis of extracts from MCF7, Hep G2, and HT-29 cells using PPP2R4 (5G3) Mouse mAb.Western blot 方法检测MCF7, Hep G2和HT-29 细胞，使用的抗体为 PPP2R4 (5G3) Mouse mAb。 |
