PRSS15/LONP1 (D8W1J) Rabbit mAb
货号：
28020S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 28020S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit IgG |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | PRSS15/LONP1 is an ATP-dependent serine protease that selectively degrades misfolded, misassembled, or damaged proteins in mitochondrial matrix. PRSS15/LONP1 is induced by hypoxic, proteotoxic, and endoplasmic reticulum (ER) stress to support cell survival (1). It has been reported that PRSS15/LONP1 inducibility is decreased during aging and chronic stress (2-4). PRSS15/LONP1 is found to be substantially elevated in lymphoma cells compared to resting or activated B cells, and knock-down or inhibition of PRSS15/LONP1 induces apoptosis in lymphoma cells (5). Mutation in PRSS15/LONP1 is associated with CODAS syndrome, a multi-system developmental disorder characterized by cerebral, ocular, dental, auricular, and skeletal anomalies (6). |
| 存放说明 | -20C |
| 计算分子量 | 106 |
参考图片Western blot analysis of extracts from various cells using PRSS15/LONP1 (D8W1J) Rabbit mAb. |
