| 货号 | 36233S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Mouse IgG1 |
| 应用 | W/IF-F/IF-IC |
| 使用方法 | WB(1:1000) IF-F (1:100) IF-IC (1:100) |
| 供应商 | CST |
| 背景 | Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, a SH3 domain, and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience-dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5). |
| 存放说明 | -20C |
| 计算分子量 | 95 |
Confocal immunofluorescent analysis of mouse primary neurons using PSD95 (7E3) Mouse mAb (green) and Synapsin-1 (D12G5) XP® Rabbit mAb #5297 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). | |
Confocal immunofluorescent analysis of rat retina using PSD95 (7E3) Mouse mAb (green) and Secretagogin (D4V1Y) XP® Rabbit mAb #14037 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). | |
Western blot analysis of extracts from various tissues using PSD95 (7E3) Mouse mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower). |
