PTPN18 (D7B9) Rabbit mAb
货号：
8311S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8311S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | PTPN18 (D7B9) Rabbit mAb recognizes endogenous levels of total PTPN18 protein. |
| 使用方法 | WB(1:1000)
IP (1:200) |
性能| 供应商 | CST |
| 背景 | PTPN18 is a member of the PEST family of nonreceptor protein tyrosine phosphatases, a group that also includes PTP-PEST and PEP (1-3). Members of this protein family contain an N-terminal catalytic domain and a noncatalytic C-terminal domain with a PEST motif that mediates protein-protein interactions (4). PTPN18 was first identified in hematopoietic stem cells (HSCs), where it was suggested to play a role in HSC differentiation (1-3). Subsequently, PTPN18 was shown to bind to c-Src kinase, forming a protein complex that functions to inhibit Src-family kinase signaling (4,5). More recently, PTPN18 expression has been shown to correlate with HER2 receptor expression in breast cancer cell lines (6,7), where it has been suggested to repress HER2 signaling (7). |
| 存放说明 | -20C |
| 计算分子量 | 48 |
参考图片Western blot analysis of extracts from various cell lines using PTPN18 (D7B9) Rabbit mAb.使用PTPN18 (D7B9) 兔单抗对多种细胞提取物进行western blot分析。 |
