| 货号 | 8013S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Rab17 (D2B2) Rabbit mAb detects endogeneous levels of total Rab17 protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization (1). Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells (2). The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis (3). Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery (4). |
| 存放说明 | -20C |
| 计算分子量 | 23 |
Western blot analysis of extracts from SK-MEL-28 cells, LNCaP cells, and mouse intestine using Rab17 (D2B2) Rabbit mAb. 使用Rab17 (D2B2) Rabbit mAb兔单抗，免疫印迹（Western Blot）分析SK-MEL-28、LNCaP细胞和小鼠肠组织中Rab17蛋白水平。 |
